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The Amariuta Lab

Methods development

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MAGEPRO
(Multi-Ancestry Gene Expression Prediction Regularized Optimization)

https://github.com/kaiakamatsu/MAGEPRO

Preprint on medRxiv (2024)

https://www.medrxiv.org/content/10.1101/2024.09.25.24314410v1

Inferring causal cell types in disease: TCSC
(Tissue Co-regulation SCore Regression)

https://github.com/TiffanyAmariuta/TCSC/

Published in Nature Genetics 2023:

https://www.nature.com/articles/s41588-023-01474-z

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IMPACT-707 for trans-ancestry PRS

https://github.com/immunogenomics/IMPACT/tree/master/IMPACT707

Published in Nature Genetics 2020

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8049522/

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IMPACT (transcription factor binding and cell-type-specific enhancer prediction)

Interact with IMPACT on the UCSC Genome Browser!

https://github.com/immunogenomics/IMPACT

Published in the American Journal of Human Genetics 2019

https://pubmed.ncbi.nlm.nih.gov/31006511/

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